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https://ulusmedj.com/index.php/pub <p>The <strong>“Ulus Medical Journal (Abbreviation: Ulus Med J)" (e-ISSN 2980-1907) </strong>is an independent, peer-reviewed, double-blind, open-access international general medical journal founded in January 2023. It is published three times a year (April, August, and December). This journal publishes Original Articles, Reviews, Short communications, Case reports, Letters to the Editor, Opinion papers, Technical notes, and Editorials. Articles are selected and published following a rigorous analysis, according to internationally accepted standards. The journal is open to scholars, as well as all members of the medical community, expressing interest in using this forum to publish their work. The official language is English.</p> en-US mdanilulus@gmail.com (Editor) editor@ulusmedj.com (Editorial Office) Mon, 23 Mar 2026 16:31:52 +0300 OJS 3.3.0.14 http://blogs.law.harvard.edu/tech/rss 60 https://ulusmedj.com/index.php/pub/article/view/28 <p>Fibroblastic reticular cell tumour (FRCT) is an exceptionally rare neoplasm arising from specialised fibroblastic reticular cells of the lymphoid stromal network. Primary involvement of bone is extraordinarily uncommon, with only isolated cases reported in the literature. We present a case of a 40-year-old woman with a destructive lesion of the proximal humerus subsequently diagnosed as FRCT. The patient was treated with neoadjuvant chemotherapy followed by wide surgical excision and endoprosthetic reconstruction. This report highlights the clinical, radiological, pathological, and therapeutic challenges associated with this rare entity and reviews emerging concepts of FRCT pathogenesis, including ectopic stromal differentiation, chemokine-driven microenvironmental mimicry, and mismatch-repair deficiency. This case contributes to the limited body of literature on primary osseous FRCT and underscores the importance of multidisciplinary management.</p> Xiang Yin Ng, Eyrique Goh Boay Heong, Adrian Teoh Zhen Yi, Shir Lee Ong, Suryasmi Duski Copyright (c) 2026 Ulus Medical Journal https://creativecommons.org/licenses/by/4.0 https://ulusmedj.com/index.php/pub/article/view/28 Mon, 23 Mar 2026 00:00:00 +0300